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Targets Recommended: HCV Protease SARS-CoV

3

抑制剂 & 化合物

15

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T6190 Telaprevir

VX-950,LY-570310,Incivek,MP-424,特拉匹韦

HCV Protease; SARS-CoV Microbiology/Virology; Proteases/Proteasome
Telaprevir (Incivek) 是一种选择性可逆的HCV NS3-4A 蛋白酶抑制剂,作用于基因 1型 (H 株) NS3 蛋白酶结构域和 NS4A 辅因子肽,Ki 为 7 nM。它也是 SARS-CoV-2 3CLpro 抑制剂。
T37022 Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt)

Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase is a serine protease expressed in the proximal small intestine of higher animals that converts inactive trypsinogen to active trypsin by endoproteolytic cleavage.1,2Enteropeptidase recognizes the highly specific amino acid sequence DDDDK on the fluorogenic substrate and cleaves after the lysine residue, releasing the AFC moiety. Enteropeptidase ...
T37021 Enteropeptidase Fluorogenic Substrate

Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase is a serine protease expressed in the proximal small intestine of higher animals that converts inactive trypsinogen to active trypsin by endoproteolytic cleavage. Enteropeptidase recognizes the highly specific amino acid sequence DDDDK on the fluorogenic substrate and cleaves after the lysine residue, releasing the AFC moiety. Enteropeptidase ac...

化合物

Telaprevir
Cat.No: T6190
Synonym: VX-950,LY-570310,Incivek,MP-424,特拉匹韦
Target: HCV Protease, SARS-CoV
Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt)
Cat.No: T37022
Synonym:
Target:
Enteropeptidase Fluorogenic Substrate
Cat.No: T37021
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-02644 Enteropeptidase Protein, Mouse, Recombinant (His & SUMO)

Tmprss15,Entk,Enterokinase,Serine protease...

Mouse E. coli
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. Enteropeptidase Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.0 kDa and the accession number is P97435.
TMPH-02643 Enteropeptidase Protein, Mouse, Recombinant (His & Myc)

Serine protease 7,Prss7,...

Mouse HEK293 Cells
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
TMPY-04626 Enterokinase/EK Protein, Bovine, Recombinant

EK, Enterokinase, PRSS7, Enteropeptidase, EC 3.4.21...

Bovine P. pastoris (Yeast)
Enterokinase is a member of the trypsin family of serine proteases. The precursor protein is cleaved into two chains which then forms a heterodimer linked by a disulfide bond. The heavy chain anchors enterokinase in the intestinal brush border membrane and the light chain is the catalytic subunit, which initiates conversion activation of a subset of pancreatic proteolytic proenzymes. Enterokinase is the physiological activator of trypsinogen and has a specificity for the sequence (Asp)4-Lys-Ile....
TMPJ-01083 Serpin E2 Protein, Mouse, Recombinant (His)

Pi7,Protease nexin I,Spi4,Pn1,Serine

Mouse HEK293 Cells
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice leads to progressive neuronal and motor dysfunction in these animals. It is also over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples whereas it is weakly expressed in all normal pancreas and chronic pancreatitis tissue samples. Ser...
TMPJ-00544 Kallikrein 7/KLK7 Protein, Human, Recombinant (aa 23-252, His)

PRSS6,Serine Protease 6,hK7,Strat...

Human HEK293 Cells
Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is to regulate the desquamation process (the shedding of corneocytes from the outer layer of the epidermis) through proteolysis of the intercellular adhesive structures between corneocytes. Dysregulation of Kallikrein 7 has been linked to several inflammatory skin diseases includin...
TMPJ-01032 SPINK7 Protein, Human, Recombinant (His)

ECG2,SPINK7,Serine protease inhib...

Human HEK293 Cells
Serine protease inhibitor Kazal-type 7(SPINK7) is a secreted protein, that in humans is encoded by the SPINK7 gene. SPINK7 contains 1 Kazal-like domain. SPINK7 is probably serine protease inhibitor. Recombinant human SPINK7 is a single, non-glycosylated polypeptide chain containing 74 amino acids and fused to His-tag at c-terminus.
TMPJ-01204 TPSAB1 Protein, Human, Recombinant (His)

TPS1,tryptase alpha/beta 1,TPS2,tryptase α/β1,tryptase α/β 1...

Human HEK293 Cells
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(TPSAB1), also known as mast cell protease 7 (MCPT7), it exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. The two Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and s...
TMPY-06036 FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)

FGFR-1,FLG,CD331,HH2,FLT2,KAL2,FGFBR,HBGFR,CEK,HRTFDS,fibrob...

Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7.
TMPK-00828 Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)

PEMT,Episialin,Mucin1,PUM,KL-6,MUC-1,Mucin-1,H23AG,PEM,CA 15...

Human HEK293 Cells
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers.
TMPK-00392 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)

CD331,FGFR-1,FLT-2,BFGFR,N-sam,FGFR1 β (IIIc),bFGF-R-1

Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession numb...
TMPK-00394 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,bFGF-R-1,CD331,FGFR-1

Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the ...
TMPK-01371 IGFBP-7 Protein, Human, Recombinant (hFc)

RAMSVPS,TAF,IGFBPRP1,AGM,IBP7,MAC25,IGFBP-7

Human HEK293 Cells
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Human, Recombinant (hFc) is expres...
TMPK-00395 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

FGF R1a,FGFR1 α,FGFR1 alpha,FGFR1 α (IIIc)

Human HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
TMPK-00393 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)

FGFR1 α,FGFR1 alpha,FGF R1a,FGFR1 α (IIIc)

Human HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
TMPY-06035 FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)

KAL2,OGD,N-SAM,CEK,FLT2,HH2,FLG,CD331,BFGFR,HBGFR,FLT-2,FGFB...

Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is P11362-7.

重组蛋白

Enteropeptidase Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02644
Species: Mouse
Expression System: E. coli
Enteropeptidase Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02643
Species: Mouse
Expression System: HEK293 Cells
Enterokinase/EK Protein, Bovine, Recombinant
Cat.No: TMPY-04626
Species: Bovine
Expression System: P. pastoris (Yeast)
Serpin E2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01083
Species: Mouse
Expression System: HEK293 Cells
Kallikrein 7/KLK7 Protein, Human, Recombinant (aa 23-252, His)
Cat.No: TMPJ-00544
Species: Human
Expression System: HEK293 Cells
SPINK7 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01032
Species: Human
Expression System: HEK293 Cells
TPSAB1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01204
Species: Human
Expression System: HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
Cat.No: TMPY-06036
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00828
Species: Human
Expression System: HEK293 Cells
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00392
Species: Human
Expression System: HEK293 Cells
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00394
Species: Human
Expression System: HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-01371
Species: Human
Expression System: HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00395
Species: Human
Expression System: HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00393
Species: Human
Expression System: HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
Cat.No: TMPY-06035
Species: Human
Expression System: HEK293 Cells
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